Take a look at each of the articles you selected in your search and answer the questions below.
1. Are the results valid?
How strong is the evidence?
What was the study design, and is it most appropriate for the question domain (refer to tab 2.Align: Levels of Evidence)?
Was there bias?
2. Are the results important?
How large was the treatment effect?
Are results clinically significant (not just statistically significant)?
3. Will the results help me care for my patient?
Does it answer my question?
Is the study's patient population similar enough to my patient (after exclusion criteria)?
4. Does this resource help me answer my PICO/clinical question well enough to write about it?
Critical appraisal worksheets are available at the Centre for Evidence-Based Medicine. Visit the CEBM website to download available worksheets that help appraise systematic reviews, RCTs, and studies addressing diagnostic/prognostic questions.
